Blair Books
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A Beautiful Taste of Historic FloridaReview Date: 2000-06-20

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Solid political biography Review Date: 2008-02-02
Parrish is the leading historian of Civil War-era Missouri. His work focuses heavily on Blair's political life, but also provides details on his subject's family life. Due to the subjects' relative obscurity and the heavy concentration on politics, this work will appeal to Civil War specialists only.

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Good read to get started and get a good overviewReview Date: 1998-07-03


A fascinating overviewReview Date: 2003-07-28
Some of the more interesting discussions in the book include: 1. The discussion on prokaryotic viruses and the use of bacteriophages as gene delivery vectors (GDV). The experiments that attempted to use lambda phages to do gene therapy in the western grey kangaroo, which is deficient in galactose-1 phosphate uridyl transferase (GPUT) (called Galactosemia in the human case) are discussed, and their failure in enabling expression of bacterial GPUT. The promise of using bacteriophage GDV in gene therapy though is discussed with examples of laboratory successes. The use of bacteriophages as antibiotics is discussed and a list is given of the things that should be remembered when considering phage therapy. 2. The use of insect viruses as expression vectors, with emphasis on the baculoviruses. The entomopox viruses are mentioned but not discussed in detail, and this is somewhat disappointing given their importance in grasshopper populations and the current plague of Mormon crickets. The genetic engineering of baculoviruses to control insects is discussed, and their efficacy in comparison to the BT toxin. The scorpion toxin AaIT gene is mentioned as one that has been used to induce paralysis in the feeding insect. Although not mentioned in this discussion, commerical products are being offered recently that make use of recombinant AcMNPV that is egt__ and expresses AaIT. Caution though is expressed by the author in the use of genetic engineering to baculoviruses due to the danger of introducing foreign genes to the environment. The ability of baculoviruses to enter mammalian cells is discussed briefly. 3. In the discussion on plant viruses, the authors discuss the need sometimes for high-level transient gene expression using virus-based vectors, instead of stable plant transformation, giving several reasons for this. Their discussion on agroinoculation is particularly interesting, especially their conclusion on "size effects" in agroinoculation. To obtain stability, genes over 1 kb in length require 'master copies" of the genome, if they are to be expressed by a TGMV-based vector. Small gene insertions, they conclude, give optimal fluidy of the viral genome, whereas large insertions do not and are unstable. However, the authors point out that viruses that encapsidate their genomes in rod-shaped particles, such as tobamoviruses, potexviruses, and potyviruses, are more amenable to larger gene insertions. The tobacco mosaic virus (TMV), was one of the first rod-shaped particles to be studied in this light, but the authors point out that recombination led to rapid elimination of the foreign sequence from the viral population. This motivated the use of more stable TMV viruses for gene expression. 4. In the chapter on mammalian expression systems, the discussion on the recombinant vaccinia virus (rVV), one of the most widely studied of mammalian expression vectors. In light of the current small pox vaccination program, this discussion took on special relevance. The authors do discuss the complications with VV strains for smallpox eradication in the context of replication-defective VV expression vectors. They also discuss the use of rVV expressing the rabies glycoprotein as a wildlife vaccine, and the Wyeth vaccine strain expressing HIV-1 gp160 for inducing HIV antibody and T cell responses. The use of the adenoviruses, for gene therapy and general research, is extensively discussed in this chapter. The authors are very optimistic in their apprasial of alphaviruses for use in molecular biology and medicine. 5. The discussion of the genetic engineering of animal DNA viruses, especially the role of herpesvirus-encoded Fc receptors for in vivo pathogenesis. The author of the article points to the tremendous role played by the genome projects for allowing the virtual prediction of gene function. The exponential increase in the use of computational biology and chemistry shows no sign of abatement, and promises even more advances in the realm of rational drug discovery. 6. The discussion of the genetic engineering of animal RNA viruses, especially the role of the techniques of reverse genetics in learning about these viruses. The genetic modification of both positive- and negative-strand RNA viruses is addressed in detail. 7. In the discussion of the therapeutic applications of viral vectors, the inclusion of the risks of gene therapy. The author is careful to point out the risks of the dissemination of transgenic sequences within human populations. Most interesting is the discussion on 'amplicons', i.e. those genomic sequences that are deleted when using HSV-1 viruses for vectors, so as to suppress their ability to replicate.
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Good book to own if you enjoy the Georgia outdoorsReview Date: 1998-03-13
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Could it be?Review Date: 2000-06-14

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Worth having nearbyReview Date: 2008-07-22

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Good Historical Compilation of Gothic StoriesReview Date: 2004-01-11
Nearly all stories were new to me; I had only previously encountered Berenice (Poe, 1835), The Body Snatcher (Stevenson, 1885), and Canon Alberic's Scrapbook (M. R. James, 1894).
Many early Gothic stories were published as though they were fragments of lost works. The first five tales in this collection are more interesting from a historical perspective than for their literary value. However, innovative writers continue to explore language, plots, and settings appropriate to this new genre. For example, while The Spectre Bride (1822, anonymous) is not entirely convincing, it does chill the reader as a young woman is seduced by a demon lover.
Within a few decades this new genre began attracting established authors. Sir Walter Scott was near the end of his remarkable career when he wrote The Tapestried Chamber in 1829. The three stories in this collection by Poe, Dickens, and Le Fanu were published in the next decade. Le Fanu's intriguing story, Strange Event in the Life of Schalken the Painter (1839), illustrates the rapid maturing of the Gothic tale.
I was most surprised by The Yellow Wallpaper (1892), a disturbing tale of obsession by Charlotte Perkins Gilman, an author unfamiliar to me. I also liked The Lame Priest (1901) by S. Carleton, Luella Miller (1902) by Mary Wilkins Freeman, and The Room in the Tower (1912) by E. F. Benson.
The introduction by David Blair provides a lengthy examination of the historical development of Gothic short stories. I initially scanned the introduction. Later, after I was better acquainted with these stories, I read the Blair's introduction more carefully as well as his brief comments on the various authors in a short appendix.

A time to live and a time to dieReview Date: 2007-05-09

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"Hang Down You Head Tom Dooley"Review Date: 2005-10-27
It would have been difficult to write this type of book about Western North Carolina without including at least a few Cherokee legends because Cherokee culture is just so prevalent in this area. Add in the occasional witch and a bigfoot or two and what you end up with is a book that is mostly legend with a few real ghost stories thrown in for good measure. Still, I liked this book.
The best and most interesting chapter in this book tells the true story behind the Kingston Trio's big 1958 hit "Tom Dooley." Tom's last name was actually Dula but was pronounced Dooley and I was surprised to find that the song is basically an accurate account of a true story. Better yet, this story actually does involve a ghost that pays regular visits to Dula's grave.
All three volumes of the "Haunted Hundred" series involve far too many stories that do not deal with ghosts in any reasonable sense. This volume is more guilty of this than the other two and really offers only two or three real ghost stories, but still I liked it. I don't know whether it is the author's obvious enthusiasm for his subject or his excellent writing style but whatever the reason, I liked this book. Now that Barefoot has finished this series of books I hope that he will go out and interview people who have had recent ghostly encounters and produce an all-new book of Tar Heel ghost stories. He has the talent and if he will give up these old legends this author could produce some top-notch ghost books.
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