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Comical at first, but works better than anything elseReview Date: 2007-11-08
Kitty-fied!Review Date: 2002-10-18
A quick nap in half the timeReview Date: 2000-06-27
Kitty-fied!Review Date: 2002-10-18
A quick nap in half the timeReview Date: 2000-06-27


Don't hire a celeb endorser till you've read Pringle's bookReview Date: 2006-10-31
Pringle Does It AgainReview Date: 2006-10-23
The best book on this subject there is.Review Date: 2006-10-21
A useful guideReview Date: 2006-10-16
Packed With Knowledge!Review Date: 2004-08-30

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A GRIPPING YARN!!!!Review Date: 2004-01-28
The Waksal-Stewart ConnectionReview Date: 2004-01-27
Compelling tale about greed and how the system worksReview Date: 2004-04-19
It is specifically about the rise and fall of one Sam Waksal, oldest son of Jewish emigrants and Holocaust survivors, a man of irresistible charm, fabulous energy, and great intelligence, a man driven to success and the high life, a man who had bounced around academia without much success until in the 1980s he saw an opportunity to become a player in the cancer game, and, along with his younger brother Harlan, founded ImClone Systems, Inc.
It is also about an anticancer drug called Erbitux, originally known as C225 because it was the 225th drug tested by its discoverers, John Mendelsohn and Gordon Sato in 1980. It showed promise because in tests it stopped the growth of tumors in mice.
And finally it is a story about how drugs get discovered, how they are developed, and especially how they get approved (or not) by the Food and Drug Administration. And of course it is about the Byzantine and incestuous relationship that exists between that August government agency and the massive pharmaceutical industry.
The curious thing about all this is that Imclone never turned a profit, Erbitux never came to market, and most of the people associated with Waksal and ImClone either made out like bandits or got stuck holding the bag. The drug itself, which works against cancer tumors, particularly colon cancer, by cutting off the blood supply to the tumors (an "antiangiogenesis" drug), was touted as a miracle that would save the lives of innumerable patients and make possibly billions of dollars for ImClone.
At least this was the hype delivered by Sam Waksal, and bought hook, line and sinker by pharma giant Bristol-Myers Squibb, and by desperate cancer patients as well as salivating Wall Street investors who jumped on the bandwagon as ImClone's stock rocketed skyward. Because of the promise of the drug, Waksal himself was able to live his dream life as a New York socialite, throwing lavish parties for celebs (including Martha Stewart while he dated her daughter), collecting fine art, popping open $600 bottles of Chateau Lafite-Rothschild while secretly selling stock on the side, sending the proceeds overseas, buying expensive apartments and houses for himself, etc., etc.
But the cold hard facts of Erbitux, like those of almost any cancer drug one can name, are very far from the hype. As Prud'homme notes on pages 332-333, "these agents...[Erbitux and others like Avastin and Iressa] are remarkable scientific advances, [but] they still only benefit some 10 to 20 percent of patients, and they only extend patients' lives by a matter of months."
That's it. That's the bottom line. And yet these drugs are so valuable that the companies that end up selling them can make hundreds of millions if not billions of dollars.
Waksal apparently came to this understanding sometime during the early eighties. He realized first the simple fact that the way the cancer industry works is doctors have to prescribe something rather than nothing. Then he realized that living a few months longer can mean a lot to people. Therefore any FDA-approved cancer drug will automatically fill a need. What this means is that the PROMISE of a cancer drug, if cleverly promoted, will spark a rally in the shares of the company that owns the patent. If, like Sam Waksal, you own millions of those shares, you can get rich on mere promise alone.
Furthermore, should the drug have any real value at all, and be approved (or even look like it's going to be approved) by the FDA, you might be able to get some pharmaceutical giant like Bristol-Myers Squibb to front a whole lot of money on that promise since they are desperate to find a cancer drug to replace those that have gone generic.
This works because even drugs with very limited effectiveness are better than no drug at all. This is true for many patients, for many doctors, and is especially true for the big pharmaceutical companies.
Note that these drugs are valuable because the people who need them are typically people of relative means who can afford to pay large sums of money for them, either through their HMOs, their government, or their own funds. In contrast a drug that would prolong the life of poor people in third world countries would be of only marginal value to the big pharmaceutical companies.
I should also mention that Prud'homme spends some serious ink in this book on Waksal's long-time friend Martha Stewart and her troubles. Her personality, her empire, and the way she handles herself are vividly detailed. In fact, some readers might find her story the most interesting part of the book.
Lively character study about Sam Waksal - needless tragedyReview Date: 2004-02-15
It is amazingly sad that all of this misery was so pointless because Erbitux has at last been approved. It almost certainly could have been approved earlier if the talented team at ImClone would have had a culture of discipline and getting things done and documented in ways that everyone knew the FDA required. If they had, all this pain and loss would never have occurred and Dr. Waksal would be a real hero instead of the one he only pretended to be.
Mr. Prud'homme writes with style and vitality. The book moves along well and has a great feel for keeping the story personal and emotionally accessible for the reader. We don't get overwhelmed with the scientific side of things, although it is always interesting to read about this emerging science and the wizards who are making it happen.
Reads like a novel, but it's a true storyReview Date: 2004-02-22
Sam Waksal, a scientist and business developer with a checkered past, lives a celebrity lifestyle, hanging out with the rich and famous, owning several fancy houses, driving fast cars, and heading a firm that is working on a cancer drug so promising that people with no other hope of treatment are flinging themselves at ImClone, begging for a merciful dose of "Erbitux."
The drug apparently does reverse inoperable tumors in a few test patients who had no other hope of living. Now the race is on to fast-track the drug through the FDA approval process based on the glowing clinical trials. But the FDA reviewer is unaccountably unencouraging when meeting with one of ImClone's top scientists. What is wrong? Is Erbitux, instead of being approved , instead going have its application refused? Why! And what will this mean for the high-flying ImClone stock?
The book reads like the best thriller, and author Alex Prud'homme is adept at making you feel like the proverbial fly-on-the-wall during the action. If you are at all interested in what happened behind the Martha Stewart debacle, you must read this. It's fantastic.

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A Great ReadReview Date: 2007-05-10
Interesting read, elegantly illustratedReview Date: 2007-05-10
Chairs; A HistoryReview Date: 2007-05-09
A Simply Fantastic Book!Review Date: 2007-05-11
the ultimate book on chairsReview Date: 2007-05-11

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great book,Review Date: 2003-09-23
Excellent serviceReview Date: 2002-06-27
Captures the pulse of business todayReview Date: 2002-03-25
A great return on your time and moneyReview Date: 2002-03-30
Will Open Your Thinking!Review Date: 2002-03-25
Peter Meyer, principal of a California (where else) consulting firm that specializes in the subject of this book, suggests a different approach. Instead of competing with everyone else, create a new market. Makes sense. As Meyer points out, it's exciting, fun, and profitable. New markets are forgiving and, without rivals you don't have to worry about competitive pricing. Can it be this easy? Meyer lays it out in Chapter One: The Mystique and Challenges of New Markets. Prepare to have your mind opened, your thoughts stimulated, your imagination titillated.
The first part of this highly readable book (type size and leading enables this book to be easily read on trains and airplanes) addresses strategies. The second part with application of the strategies. Good model for this highly practical book.
The other chapters of the first section deliver ideas, perspective, and examples of how the strategies have been used. Balancing Your Resources and Opportunities. It's the Problem That Matters. Choosing the Best Risk. What New Markets are Available to You? Are you beginning to get a sense of the depth of content of this book?
The book is written in relatively short sections, so the reader never seems overburdened by the volume of text. I kept slowing down...because I was thinking about what Meyer said. Then I found myself taking notes, like I was starting to write a business plan. See what I mean? I predict that you'll read this book at least twice: once for a quick overview, then at least one more time (with Peter Meyer at your elbow) thinking, talking to yourself (and others), and constructing ideas that may drive your future.
Charts sprinkled throughout the book will guide in your understanding of the message. So will the questions tossed out by the author. There are many paths to take in creating, exploring, exploiting, and dominating new markets. Each alternative approach has its advantages and disadvantages. Your strength will come from understanding what's involved in your journey, and that power will come from this book.
Section Two concentrates on the application of the strategies. Funding the New Market Effort. What Role Does the Customer Play? Building and Dominating Markets Through Involvement. What is the Role of Information Technology. Using Credibility in Creating and Dominating Markets. What's Next? And the book closes with a good index to help you find what you want on your second and third readings.
This is the new frontier. You can be on the leading edge. It's a different world, as Meyer warns. If you think you're up for it-and the book will help you determine that readiness, this book will be your guide.
Now my review is done. I'm going back for my second helping!

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A tremendous resource for building power brands.Review Date: 1999-08-22
This book has worked for me!Review Date: 2001-03-25
Highly Recommended!Review Date: 2001-03-21
A must for marketing, advertising & branding executives.Review Date: 1999-10-09
The guidance, tools, templates and forms provided in the book give you everthing you need to develop a positioning for your brand and to communicate your brand's essential value proposition. Advertising agencies and public relations firms should pay their customers to read this book!
Perfect for Everyone in Brand ManagementReview Date: 1999-12-04

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Little GemReview Date: 2002-11-06
Two things bothered me though. Emily did not tell us enough about herself. I would love to know her approximate age and more about her human family. Also, I thought the 9/11 information was distracting, and made the story too "current event". If those two pages are deleted, the book will regain a noncontemporary feel, and should be enjoyable for many years to come.
I would love to read a sequel.
Dear DollyReview Date: 2002-11-06
I was raised on a farm in the state of Virginia with horses, cows, pigs etc.
I would recommend this book to anyone who has a love for animals be it horses dogs or cats the true love for the animals comes through.
This book also shows the care and love you must give to our 4 leg friends.
I shall look forward to another book by Emily Bridges in the future.
IT'S ABOUT MORE THAN HORSES... A Great Gift Book!Review Date: 2002-10-23
A REAL Horse BookReview Date: 2002-10-28
RefreshingReview Date: 2002-10-26

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A Definitive History Of A FailureReview Date: 2003-06-22
A KeeperReview Date: 2004-05-23
Interesting history of a controversial carReview Date: 2004-05-05
This book is a great read, and the illustrations include many interesting design proposals. I would have given the book 5 stars if the illustrations had been printed on coated paper and included at least a few in color.
Disaster in Dearborn: The Story of the EdselReview Date: 2003-08-28
A comprehensive yet concise history of the EdselReview Date: 2003-01-23

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Great BookReview Date: 2007-10-01
it is a very good book for a beginning student of BBA OR MBReview Date: 1999-03-19
Full of ItReview Date: 2002-03-13
An easy to read useful book and not only for BusinessReview Date: 2007-01-09
Wonderful reference bookReview Date: 2003-12-13
Beyond that, the AIDA approach to business writing is clear and easy to use once students get the hang of it. My students' major project is to work with an organization in solving a communication problem, they are responsible for writing memos and reports to both the client and me.
However, I guess that the biggest endorsement is the number of students who do not resell this book at the end of the semester. I have had several tell me that this is one of the few books that they will take with them when they graduate because they view it as a good reference book.

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Finally, an easy food guide!Review Date: 1998-11-07
Excellent !Review Date: 1998-08-24
Excellent!! Provides a simplified strategy for healthy dietReview Date: 1998-08-14
OutstandingReview Date: 1998-07-11
The Food Report CardReview Date: 2001-02-01
"You can make an enormous impact on your long-term health, and even on your appearance," Dr. Yannios writes, "if you do nothing else during your normal food shopping but select the A- and B-rated foods, and leave the C's and D's on the shelves back at the store."
Dr. Yannios believes that atherosclerosis (hardening of the arteries) is the number one health problem for many Americans. He says that "food significantly impacts" atherosclerosis, and that we can reduce the negative impact by carefully choosing what we eat. "People are confused," Dr. Yannios says, explaining that he wrote The Food Report Card to help eliminate confusion and enable people to choose foods that are good for them.
He has grouped foods into categories, such as beverages, cereals and grains, milk and dairy products, and meats. Each food within a category is then listed in alphabetical order, such as chocolate milk and vegetable juice in the beverage section. Foods are then evaluated by brand name. For example, five brands of vegetable juice are analyzed and graded. He maintains that pattern for each food category, analyzing 12,000 foods altogether. All you have to do is look up a specific food to quickly determine whether it is an "A" food that you want to consume or a "D" food you want to avoid.
People who want to choose the healthiest processed foods, but don't want to spend a lot of time calculating nutritional values from confusing labels, will find The Food Report Card informative and helpful.
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