Pharmacy Books
Related Subjects: Nuclear Pharmacy Directories Schools of Pharmacy Drugs and Medications Pharmacies Prescription Services Organizations
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Used price: $68.49

Can't believe a PharmD wrote this stuff!Review Date: 2007-06-11
Editor NeededReview Date: 2003-04-14
Used price: $7.15

Sorry I ordered this reference bookReview Date: 2007-02-13

CAUTION!! WAY OUT OF DATEReview Date: 2005-09-27


Helpful only as an overall reference to the PCATReview Date: 1999-04-28

Used price: $0.01

Nothing newReview Date: 2007-02-13
Used price: $0.64

For your informationReview Date: 2005-07-06
PRESS RELEASE
For release, April 9, 2003
Cassim Igram, D.O., a 47 year-old physician from Batavia, Illinois, entered into a Settlement Agreement
with the Board to resolve pending disciplinary charges. Dr. Igram was charged with being disciplined by the
Illinois Medical Board. The Illinois Board accused Dr. Igram of engaging in unprofessional, unethical and
dishonorable conduct in his care and treatment of several individuals who sought nutritional consultation.
Dr. Igram was fined $4,000 and his Illinois medical license was placed on permanent and irrevocable
inactive status. Under the terms of the Iowa Settlement Agreement, Dr. Igram must provide the Board 90
days written notice and fully comply with any and all requirements established by the Iowa Board prior to
beginning the practice of medicine under his Iowa medical license.


Don't waste your money.Review Date: 2003-10-01
This text is neither a stimulating nor accurate source of information on pharmacy law and ethics. Look elsewhere.

Used price: $63.87

DisappointedReview Date: 2007-07-17

Used price: $0.43

Waste of Money!Review Date: 2006-11-06

Used price: $99.25

Misleading ExpertiseReview Date: 2003-10-07
withdrawn 8/01), fluvastatin (Lescol™), lovastatin (Mevacor™), pravastatin (Pravachol™), simvastatin (Zocor™),
pitavastatin and rosuvastatin (Crestor™), which were introduced to lower total cholesterol (TC) levels, and especially
LDL-cholesterol (LDL) levels, ostensibly to prevent coronary heart disease (CVD).
The book consists of 8 chapters by nominally highly
qualified authors in the form of review articles of the sort
normally found in medical journals. These are devoted to
the pharmacology and supposed benefits of statin drugs.
The writing is in expert medical language and is consistent,
well-written, well-edited and very well-referenced, in
quantity if not in quality. The index is inadequate.
All
chapters attempt to justify the wide use of the statin drugs to lower TC and LDL by citing references in support
of the
claims that high levels have been correlated with cardiovascular disease (pp1,19,35,81,84,99,121,126). Such
claims are
unfounded (Ravnskov U, The Cholesterol Myths, Washington, DC, New Trends, 2000).
The supposed benefits of the statins,
beyond a large, but meaningless lowering of TC and LDL, are usually given
as lowered relative risks (RR) of mostly non-fatal
heart attacks without the slightest indication of the magnitude of the
more meaningful reduction of absolute risk (pp101,103,106,115,122,124,137).
This misrepresentation has been
noted (Ravnskov, 2000; Gigerenzer G, Calculated Risks: How to Know When Numbers Deceive
You, New York,
NY, Simon & Schuster, 2002). So the usual tout of pravastatin in the WOSCOPS trial of a 22% drop in all-cause
mortality was noted without the information that this was only an 0.9% drop absolute in the 5-year trial period
(p106).
The higher all-cause death rates in 2 of the big trials were ignored, as was the higher breast cancer rate (RR
= 1500%)
in the CARE trial (Ravnskov, 2000).
Besides cancer, the other side effects of statins listed were incomplete, and should
have included myalgia,
myopathy, polyneuropathy, liver and kidney damage, congestive heart failure and amnesia. Side-effects
were said to
affect 2% of patients (p115-6) and 2-6% (p123). In fact, a recent review noted side-effects in 20% of patients
above
the placebo rate, and no change whatever in the all-cause death rate for atorvastatin (Newman CB, Palmer G,
Silbershatz
H, Szarek M. Safety of Atorvastatin Derived from Analysis of 44 Completed Trials in 9,416 Patients.
Am J Cardiol 2003;92:670-6).
Statins decrease the body's production of the essential coenzyme Q-10 and dolichol, among other things. This
was not
mentioned as a problem in any chapter. While this was shown in one biochemical diagram (p65), it was not
in another (p82).
Low Q-10 levels are strongly associated with congestive heart failure.
"Statins are contra-indicated during pregnancy
and breastfeeding. The reason for this is that cholesterol is an
essential component for fetal development, including
the synthesis of steroids and cell membranes" (p116). The
authors seem unable to comprehend that cell membranes, steroids
and coenzyme Q-10 are needed by all humans.
The rare familial hypercholesterolemia, in which TC > 400 mg/dL, was represented
as more deadly than it really
is (p99,111), (Ravnskov, 2000).
There was some recognition that statins operate to
lower non-fatal heart attack rates by mechanisms other than
cholesterol lowering, but not that their desirable effect
on thromboxane A2 is less than men can obtain with buffered
aspirin (p71), or that the desirable effect of raising nitric
oxide (NO) levels is less than one can obtain with the
supplement L-arginine with no side-effects. There was no understanding
that these effects of statins are independent
of initial or final TC or LDL levels (Nielsen JV. Serun lipid lowering
and risk reduction? Where is the connection?
Br Med J Rapid Response, 19 Nov 01, to Kmietowicz Z. Statins are the new
aspirin, Oxford researchers say. Br
Med J 2001;323:1145), and thus there is no way to determine who should be treated,
or what the dose should be.
An entire chapter is devoted to the cost-benefits of statin use (p138ff). Since the use of
statins for primary
prevention of CVD has been shown to increase all-cause mortality by 1% over a 10-year period (Jackson
PR, et al.
Statins for primary prevention: at what coronary risk is safety assured? Br J Pharmacology 2001;52:439-446),
and statins
have very little effect in secondary prevention, it would seem that there is no cost-benefit (Kauffman JM,
"Do
Hypolipidemic Drugs Lower Medical Expenses?" Pharmacotherapy 2001;22(12),1583-1586).
This book may be of use for a pharmacologist looking for an overview, however narrow in outlook, with literature citations.
---Joel M. Kauffman, 6 Oct 03
Related Subjects: Nuclear Pharmacy Directories Schools of Pharmacy Drugs and Medications Pharmacies Prescription Services Organizations
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On page 259 in Pharmacy Practice it states, "add 100 units Humulin Regular Insulin to D5W 500 mL @ 20 mL/hr". Insulin is for diabetics. Diabetics do not have the insulin to store and breakdown sugar. Why would we put the insulin into D5W (dextrose 5% in water). Dextrose is a SUGAR! The patient's blood sugar needs to be corrected quickly. Why would we put the insulin into 500 mL?!
On page 48 in Pharmacy Practice the label for gentamicin is wrong. It reads 20 mL=80 mg. It should read 2 mL=80 mg. Big difference.
The total number of errors is too numerous to mention.
I can hardly wait until Jan of 2008 when our contract will be up and we can return to our Mosby Pharmacy Technician textbook.
Don't buy this book. It a waste of $$.