Works Books

"Wonderful, wise words. It provides insight into the human side of serious illness and offers patients and families the hope and strength they need." Jimmie Holland, chairman Psychiatry, Memroial SLoan Kettering

"Filled with practical information for freinds and family, it should prove to be a great comfort..." Andrew von Eschenbach, director, the FDA


"...Provides hope and teaches us how to show compassion when it means the most." Steven Rosen, MD, director of the Lurie Cancer Center

This was the book I was searching for to help my best friend. It spoke to me because of the way the author told her personal story and gave ideas and suggestions. I felt like she was speaking to me.

She knew what I was feeling, knew I wanted to help and she gave me ways to do that. She helped me face the future right beside my friend.

when Life Becomes Precious was a godsend. It should be handed out to everyone at doctors' offices.

This truly is a fabulous resource! The information is quite straightforward and covers a wide array of areas/issues that are certain to be impacted by the news of a loved one being ill. The components of the book cover areas such as understanding your feelings, how our fears play out in the ordeal, how to have conversations regarding the illness and ramifications of the illness, how to find resourceful medical care and how to balance one's role in life given the situation.

I would highly recommend this book for people who are going through the challenge of a loved one being ill, as it applies to not only cancer patients - but all who have serious health issues.

Elise Needell Babcock's words are better than any I've read on dealing with cancer and family. Her advise is simple and extremely helpful.

My spouse had heart disease. At the same time, I was looking for a book for a friend with cancer. I found Precious and read it before giving it as a gift. I realized the suggestions applied to my family. I started using the author's ideas immediately and it helped us tremendously. I find myself quoting her often in my volunteer work at church (with patients) and with friends. One friend called and said she was having serious problem coping with her husband's diabetes. She read the book and called to tell me that after following the advice in Precious, she saw a dramatic change in the way her family communicated and supported each other. Another friend said she was in an argument with her daughter about the father's illness. The mother used the suggestions in the book to calm her daughter down. Later that evening, the daughter (in her 30s) came up to her mom and said, "Thank you. What you said and how you said it was wonderful!" This book should not even have cancer on the cover. It's practical, moving, upbeat and extremely helpful for patients and families coping with any medical challenge. J. Long, past president of a personnel agency

March never leaves my desk. It covers everything. From functional group transformations to mechanisms to FMO theory - you name it it's there. Highly recommended for any advanced undergraduate, graduate or post-doctoral researcher. It's a bookshelf staple that any organic chemist should have available.

I'm pretty sure that you _must_ have this book if you are studying advanced organic chemistry. Maybe it's not the best one to use as a study guide, but it's extremely helpful as a reference book both for undergrads and graduate students. However, one can argue that this edition is a bit out-of-date.

I bought a copy of this text (2nd Ed) after finishing my sophomore year of college, and it proved to be the best single investment I've ever made in chemistry. I used it so often, I had to duct-tape the book together.

I think the happiest moment of my career was when my name appeared in the index of a later edition. Anyway, buy it and treasure it.

This is by far the best text I have found. Although it is considered a text book, it is more handy as a reference tool. I have seen no other book that contains more information than March's. This book is actually worth the price.

I paid more for my 4th ed. new, and find it to be worth even more. It is not a cookbook per se, but it is a very comprehensive textbook that details general reactions by functional group. It outlines every way known to remove, add to, or otherwise modify every functional group. There is as much commentary as is needed, if not more, and every pathway is mentioned regardless of how exotic or primitive and low-yielding. The corresponding OS synth refs for specific cpds. are given for each type of reaction, along with a total of 15,000 other refs in footnotes. This was cutting-edge in 92, with much updating of the 3rd ed. The index will take you to the section that shows how to make the manipulations you want - if it doesn't, it probably can't be done.

The Andropause Mystery, Unraveling the Truths About the Male Menopause by Robert S. Tan M.D.

In this book, Robert Tan MD , an astute clinician and a board certified specialist in geriatric medicine, describes his professional experience, diagnosing and treating hormonal decline in aging males. Tan describes a turning point in his career when he stumbled upon a bedridden male with the typical signs and symptoms of low testosterone, namely muscle weakness, frailty, memory loss, and hair loss. Lab testing confirmed low testosterone levels. Testosterone for aging males was new in those days, so Tan had difficulty convincing the pharmacy to release the testosterone injections ( 200 mg twice a month). After three months of injections, the patient grew a beard, began walking again, and his memory and libido improved.

The experience motivated Tan to do a Medline search on the topic, and he found very little research in the area of Male Menopause, also called Andropause. This book was written to unravel the truths and dispel the myths about the Male Andropause and Testosterone replacement for the aging male.

Tan asks a few obvious questions. The medical system treats women for the hormonal decline of Menopause, so why aren't men treated for their similar hormonal decline of male Andropause? The medical system recognizes Menopause, but does not recognize Andropause.

Many physicians deny that Andropause really exists. Tan says sorry, but it does exist, and his patients are testimony to this truth. Andropause is a real syndrome, and he clearly explains that 30% of males over 65 have low testosterone levels with the associated muscle weakness, memory loss, and loss of libido. Tan also explains the reasons why the syndrome is ignored by conventional medicine. There is no curriculum in medical school or residency, and very little research in the library due to lack of funding, and lastly, unlike females who are more expressive and communicative about their night sweats and hot flashes, males tend to be stoic, and in denial of their Andropause symptoms.

Tan discusses the beneficial affects of testosterone on cognitive function, finding that many (but not all) demented nursing home males are restored to normal after testosterone treatments. He also discusses the effect of testosterone on mood, cardiac function, muscle strength, bone density, and lastly improvement in libido and erectile function. In one humorous story, Tan recounts a demented nursing home patient whose testosterone treatment had to be discontinued because of hypersexual effects. Apparently, the old fellow had approached several nurses with inappropriate requests.

Tan also discussed the incorrect belief that Testosterone treatment increases the risk of prostate cancer. Tan dispels this myth, stating that in his clinical experience, he has yet to see a case of prostate cancer induced by testosterone replacement. Nonetheless, Tan advocates routine prostate surveillance with serial PSA and DRE.

Chapter 7 discusses the nuts and bolts of testosterone replacement with diagnostic blood testing, available testosterone preparations and dosage schedules. Tan feels that testosterone replacement for males should become as routine as HRT for the female menopause.

Inconclusion, in a field with scant information, Tan's book fills a void. The book is an honest, courageous, down to earth, and occasionally humorous look at testosterone replacement for the aging male. Also recommended is The Testosterone Syndrome by Eugene Shippen MD.

Jeffrey Dach MD

What I thought I bought; a book about the aging process and the Andropause. What I got; mostly a book about testosterone replacement. This book was a let down.

The bravado of patriarchy and its reliance upon presenting males as strong, vibrant creatures able to take on the world when young, and equally powerful when old has always been a myth perpetuated as the alpha male syndrome.

However, the reality is that, like women, men undergo similar hormonal changes as a result of aging. While the outward appearance of men may remain somewhat similar, both personality and hormonal changes occur along with the physical changes in muscle power that young men discern readily in challenging the older male establishment for power and prominence.

Little discussed, or viewed as the natural aging phenomenon of men and the mellowed perspective in which he sees the world, and operates in it, typical male menopause has focused upon his desire to grativate toward younger women to extend his male prowess, or by making the wild changes of adopting fast cars, and more relaxed lifestyles in an attempt to capture his youth.

That males haven't come to grips with the similarities of aging among women ought to be a concern since so much of society is organized not around the vitality cycles of natural aging, but by the fantasies of aging men who deny their own mortality, and the consequences of aging. Taught to view women differently, men therefore find it more difficult to accept their own aging process because of the enormous differences in how men and women are cultured to be viewed by a male dominant society.

Because men died at somewhat younger ages throughout life, the lifecyle phenomenon of men has never been approached with the legitimacy or credibility that is a part of the natural consequence of being male.

That either men or women are taught to view the aging process as one that is devalued because of its physical changes rather than prized for its contribution to stable and sustainable populations is a social problem that has yet to be taken seriously. When country singers sing that "all my rowdy friends have settled down," they are recognizing this natural tendency of men to settle into a lifestyle that accepts their aging as natural, and normal rather than continuing to idolize the rowdy lifestyle that the constant pumping out of male testosterone helps to create.

The message, of course, is that, like women, men will not live forever, do suffer the consequences of aging, and must adapt age appropriate lifestyles that respects their aging, rather than condemns it. That attitude will work for both men and women to help define the expectations of being human, and mature as individuals, in planning their lives and knowing what to expect from their bodies, and what not to expect.

This book is really for the layperson. The book "Andropause Mystery" does describe evolving physical, sexual, psychological and mental challenges encountered by the aging male. It does explain hormone replacement for men and the potential problems. There is a nice chapter on the psychological impact of aging on sexuality. It is easy to read and understand, but I prefer "Aging Men's Health: A Case Based Approach" by the same author. No doubt, it is a textbook, but there is more depth and detail for the professional person.

I couldn't believe it! The controversy about hormones for women has begun, now men? The book and author was featured on NBC Nightly News on 7/31/02. Guess it must be an important topic to be on national news!

I LOVED this book. Lydia uses tons of references and provides the reader with varying opinions on acne. She readily admits that there isn't one universal cure for acne and her research is extensive. I recommend this book to all of my clients who suffer from acne. There is a comprehensive bibliography as well where you can find books with more in-depth information.

I enjoyed this book, but I think pictures would be useful to clarify the text.

After finding myself trying several OTC programs which didn't work, I stumbled across this book. I had no idea that I had been using BP all wrong! FYI, BP is not a spot treatment for pimples with white showing. I also had no idea that salicylic acid products had to be of a pH between 3 and 4 to be most effective. I wish the author would have tested more salicylic acid products for the appropriate pH. Only a couple of the ones she tested had the requisite pH. I would have much rather had a large list of products with the recommended pH than a large list of products without it. Also, I agree with a previous reviewer that pictures would be most helpful, especially in describing the formation of acne and what the different kinds of acne look like. Overall, I found that this book is a good introduction to the world of acne, but definitely not a place to stop learning.

Do you believe that if a product dries out your face, your skin will overcompensate by producing more oil? Do you think a special scrub can unplug your pores and help free you from blackheads? Or maybe you cherish the belief that you can sweat your pores clean of acne-causing dirt or toxins through vigorous exercise or steam treatments? If so, you need to read this book.

I have never realized how poorly I understood acne, and I am amazed how many myths I let myself absorb from "informative" commercials and advice given by well-intentioned editors of numerous women's magazines. I am immensely grateful to the author for teaching me what acne is - really and exactly - and for doing so in an accessible and friendly manner. Just the chapter "Understanding Acne" alone is worth the money I spent on this book, because it's hard to fight the condition without understanding it, and because it simply feels good to know for once what is going on with my skin.

I have had cystic acne since I was a teen. I'm now 42 and there are no signs of it going away. I see a dermatologist regularly. I have tried literally hundreds of skincare products.

I purchased this book, read it cover to cover, and changed my skincare routine in response. I am using products I already had - a mix of OTC and prescription items - I just didn't have a good plan for using them.

To my amazement, I have now gone six weeks without a cyst. This may be the longest cyst-free period in my adult life.

Lydia Preston, you are my hero.

UPDATE: Three months, no cysts. I could seriously cry!

When I was diagnosed in 2005, I was absolutely overwhelmed with fear, information, and decisions. This book is the only one I found that made sense to me. It is clear, concise, and very encouraging. Dr. Link's approach is from a place of genuine respect and regard, and he knows exactly what survivors need to know right away. Reading this book really helped me make the best treatment decisions for myself, with the best information available. The book teaches survivors (who for the most part are not medical professionals, but will unfortunately have to get to that level pretty quickly) how to read pathology reports, and helps you formulate the questions you need to have answered to make your choices. I recommend it to everyone I know who is newly diagnosed.

Very good basic guide for one suffering from breast cancer, one problem was that it was 8 years outdated. Would have been better had it been updated, new treatments are always being discovered. It was a good overview, though.

A book for those who are newly diagnosed with cancer. The book describes in detail the different stages of breast cancer. It also discusses how individuals should see doctors for a second opinion. Another great part about the book is the differences in opinion about how to manage breast cancer, and the different paths to take.

I bought this book when my mother was diagnosed with breast cancer. The first advice it gives was a breath of fresh air in the middle of a maelstrom. It simply said "you have time." It also gives great advice on second opinions. Besides this first advice the book is filled with general information written in easy to understand english. Some of the info applies some of it doesn't, everyones cancer is different. I greatly recomend this book to all those of us faced with this challenge. It provides you with the information doctors usually don't take the time to give you. A must read before your next doctors visit. One caveat: if you are looking for a feel good read this is not it... this is a serious book of medical information.

I just had this mailed to a friend who was recently diagnosed with very aggressive Breast Cancer. She is only 41. When I was 41 in 2000, I was also diagnosed. This book helped me so much! It is informative and easy to understand. It is not a dry read, like other books on this subject. Most importantly, it is not a downer. While this book is realistic it is also upbeat. I tried reading Dr. Susan Love's book and it was so depressing I could only read one chapter.

This is the definitive guide for breast reconstruction. It covers every type of reconstruction, is fair and balanced and VERY readable. It takes a complex subject and really makes it easy to understand. When you are facing such an emotional decision and hard surgery - it helps tremendously to have information to help guide your decision making. This book is it. Highly recommended before you consult with your first surgeon.

I bought The Breast Reconstruction Guidebook several weeks ago and it has been an incredible resource! Due to a genetic mutation (BRCA2), I'm preparing for bilateral prophylactic mastectomies. The Breast Reconstruction Guidebook clearly explains mastectomy and reconstruction procedures, questions to ask my potential surgeons, how to prepare for surgery, and what to expect during my recovery. Kathy Steligo's book has helped me sort out my options at a very scary time, and for that I am truly grateful!!

This book became my bible during my recent surgeries. So much so, that I broke the binding reading and re-reading it. It offers something for anyone remotely affected by decisions surrounding breast reconstruction. In a world where we can sometimes find too much disjointed information on the internet, this book nicely summizes the facts with an appropriate level of detail. Thankfully, this book was available when I needed it!!

Excellent book. Very informative, so much so that my plastiic surgeon will be ordering a few for his other patients. Knowledge is power and this book will replace the fear with empowerment.

This book is great to read if you are contemplating a mastectomy and reconstruction. Its info was great to know before consulting with plastic surgeons and choosing the right one for me. The practical suggestions of preparations and after surgery suggestions make me feel more confident about what is ahead.

My 6 year old loves reading this book. It shows how children around the world dress, live, and play. It is interesting to see what other children like to do for fun, or what they like to eat. It is also teaching her about the different countries around the world.

This awesome book shows children around the world and what their everyday life is like (homes, schools, families, pets, friends, churches, food). Having a daughter adopted internationally,this book helps us learn more about her birth country and about all the children of the world. We've started giving this as birthday gifts to her friends.

I hope that all children can someday enjoy this book with their friends and caring adults. It makes real the lives of children all around the world - their hopes, their dreams, their families and their daily routines. It's a delight to see our similarities and a great lesson to learn about our differences. Thank you to the authors and publishers.

My family and I love this book so much I bought one for every set of cousins on our Christmas list. Our three year old daughter doesn't watch TV so this is a fantastic way for her to get a sense of the wider world....She's fascinated by the photos and stories of the children who dress and live so differently from her. And our older cousins can read the materials themselves. We very enthusiastically recommend this one!

I purchased this book for my son Ben when he was 2 1/2 yrs. old. He is now 10 and my daughter Maria reads it continuously. This book is by far the best young children's awareness book about the differences and similarities between all children on this earth. I work for the YMCA and have purchased it for our summer camp so that the children coming to stay at Camp Silver Beach can learn more about the childhoods of the international counselors who are role models for them during the summer. At 2 1/2 years, my son knew the continents and could point out where "Ari or Celena" lived and tell me their favorite toys or food and point to the countries in which they live. This book is colorful and timeless expanding a child's view of the world and helping to instill the compassion we need to get along with all kinds of people.

I was very disappointed with this book. It held my attention for the first 100 pages and afterwards went downhill. I felt I could relate to the stories in the beginning but after that it just seemed like nonsense. I think I was looking for a man to bridge the gap between women & men with miscarriages. Or maybe I was looking for more medical information and what is being done. I defintely did not find either of those topics in this book.

I could not put this book down. I found it to be extremely helpful and therapeutic.

This book gave me clarity and peace after suffering from 2 miscarriages. I refer to it often when I need some guidance and explanation. A must for all women who have experienced one or more miscarriages.

After his wife miscarried four pregnancies, author Jon Cohen poured effort into assembling a comprehensive, accurate, and user-friendly repository of information on miscarriage. Now in a new paperback edition that corrects a few errors found in the original, Coming to Term: Uncovering the Truth About Miscarriage explores the latest research and findings on the phenomenon, debunks myths and hype, and shines a spotlight on real problems that could be making the occurrence worse in today's world - such as federally unacceptable nitrate levels (which fluctuate seasonally, often influenced by agriculture and animal waste disposal) found in some American wells. Cohen also explores a diverse array of medical treatments, from drugs to surrogate parent contracts to "touchy-feely" emotional therapy methods that can offer surprisingly positive results. Steeped in compassion as well as wisdom and solid information, Coming to Term is highly recommended.

There are several reasons why this book does not deserve its present "five star" rating which are explained in this detailed review. The primary criticism is that the author demonstrates a lack of understanding of the scientific literature. He also shows a lack of scientific insight, and fails to recognize how immune issues can play a role in reproductive failure. He also uses a (now widely considered) flawed study to support his central arguments. Finally, he criticizes reproductive immunologists for their use of anecdotal evidence, yet relies on heavily anecdotal evidence to support his own views. In more detail, here are the weaknesses in this book:

On IVIG treatment for recurrent miscarriage

Cohen chooses to elaborate on the negative sides of the IVIG argument, yet fails to elaborate on the positive arguments, a disservice to the reading, investigating audience trying to understand all sides of IVIG issue.
For example, he agrees that elevated natural killer cell levels can be associated with miscarriage. On page 95, he says: "...studies suggest that women who repeatedly miscarry chromosomally normal babies produce higher level of natural killer cells." Cohen also agrees that IVIG may suppress natural killer cells. Page 95: "Some experiments show that IVIG suppresses natural killer cells" Yet, despite his acceptance of an NK miscarriage connection, he still chooses to scare patients away from lifesaving IVIG treatment that many clinics offer. On page 95 Cohen says "IVIG inadvertently infected people with hepatitis C" and "no amount of screening can test for a pathogen that science has yet to discover." Also, Cohen fails to mention the fact that modern IVIG preparations are screened for all known viruses, past and present. And fails to emphasize that IVIG is completely FDA-approved and thousands of patients are using it routinely with no ill effect for dozens of common autoimmune diseases. For a professional reporter supposedly reporting all sides of an issue, Cohen's investigation seems surprisingly one-sided.
Finally, Cohen seems to criticize the mental state of any patient choosing the IVIG option. At the end of page 95, he states: "untried options can have an intoxicating effect, leading them (women) to throw caution to the wind." I think Cohen's personal bias against reproductive immunology is clear. His ability to report on IVIG with logic and impartiality is sacrificed.

Th1:Th2 theory

On page 79, Cohen states that Th1:Th2 (immunological rejection) theory is a "hugely controversial hypothesis." However, most people who read scientific reproductive journals today would wonder how Cohen arrived at this understanding of the miscarriage literature. If he had a proper grasp of current theory he would not see that the Th1:Th2 theory is not only not "hugely controversial," but it is actually one of the freshest and most accepted new research developments in reproductive immunology medicine today.
How does Cohen arrive at his "Th1:Th2 is controversial" conclusion? In the book, Cohen cites only one single Th1:Th2 review study by Laird SM et al. (he apparently ignores the rest of the rest of the supporting studies in the literature) Yet, interestingly, upon reading carefully, this study actually seems to support Th1:Th2 relevance to miscarriage. It states: "Immunological rejection of the fetus due to recognition of paternal antigens by the maternal immune system, resulting in abnormal immune cells and cytokine production, is postulated to be one cause of unexplained pregnancy loss...there is some evidence for an alteration in the ratio of Th1 and Th2 cytokines produced by peripheral blood monocytes."
Note the phrases: "evidence for an alteration in the ratio of Th1 and Th2 cytokines" may be the "cause of unexplained pregnancy loss." So Cohen's strongest study against Th1: Th2 theory actually seems like it does not bolster his argument much at all?

Antiphospholipid Antibody (APA) Issues

On page 96, Cohen implies that APA positive recurrent miscarriage patients are like a "Black Swans" meaning that, although these patients exist, they are not as common as people might think like (they are rare and over-sensationalized). Again, it appears Cohen is "off the mark" here too. In fact, any layperson who does a cursory Pub-Med search through the literature would find that APA miscarriage patients are actually very common in the recurrent miscarriage population. In fact, one study shows that APA positive patients are present in almost a third of ladies who suffer unexplained recurrent abortion. See study by Cubillos J et al, Incidence of autoantibodies in the infertile population." Obstet Gynecol. 1997 Sep;90 (3):364-9 which states: "In the group of patients with a history of miscarriage, 38.2% (p < 0.05) (tested positive) for APL."
In addition to failing to state the truth about APA frequency, Cohen fails to address the fact that very few centers do the proper APA testing. This may account for why so many APA patients are missed in many infertility clinics. Few local laboratories test for all 6 classes of APA, causing many APA positive patients to be missed: See study by Coulam CB et al: Antiphospholipid antibodies associated with implantation failure after IVF/ET. J Assist Reprod Genet. 1997 Nov;14 (10):603-8. Study quote: "A complete APA panel using seven isotypes is necessary for diagnosing implantation failure associated with RAFS. If only anticardiolipin antibody is measured, 4% (13/312) of the positive APAs are detected, and 81% (56/69) of women with implantation failure associated with RAFS will have the diagnosis missed." Cohen never addresses any of this.

Endometriosis

On page 44, Cohen asserts that no miscarriage/endometriosis connection exists.
Cohen's words: "...controlled, randomized prospective trials later convincingly showed that no such connection exists." However, the truth is, there are dozens of studies in the literature citing the connection between endometriosis to immune issues early pregnancy loss. Does Cohen simply not know these studies exist? Or just he just over-look these studies, instead? Doesn't Cohen ever wonder about the "coincidence" that endometriosis is closely tied to immune issues and is also connected to recurrent pregnancy loss? Has he ever thought that there may possibly be a connection between endometriosis and miscarriage? Once again, Cohen seems naive to the literature and totally naïve to the larger interrelated implications that individual, so-called "unrelated" studies can present. Not only do Cohen's assertions about endometriosis seem naïve, but his assertions seem weak as well. His arguments are based on one single study: Vercammen EE et al: Endometriosis and recurrent pregnancy loss. Semin Reprod Med. 2000;18(4):363-8.
Upon reading the fine print of the study, you find that the argument against the recurrent miscarriage/endometriosis connection is not even that strong to begin with. The authors (countering what Cohen might imply) actually suggest that endometriosis is associated with implantation failure...yes... the very study Cohen uses as his argument against such a connection makes such a connection! See study quote: "...some studies have shown that the decreased number and quality of oocytes, the fertilization rate, and the implantation rate per embryo may be reduced in women with endometriosis"

The Polycystic Ovary Syndrome Issue

On page 114, Cohen states "The largest studies to date of pregnant women with PCOS estimate miscarriage rates of 40 percent and 60 percent." Yet, Cohen misses the connection between PCOS miscarriages and immune issues completely. There is one important immune-PCOS study that he omits entirely by Jakubowicz DJ et al: Reduced serum glycodelin and insulin-like growth factor-binding protein-1 in women with polycystic ovary syndrome during first trimester of pregnancy. J. Clin Endocrinol Metab. 2004 Feb;89 (2):833-9. Study quote: "These findings are significant in that they may provide a mechanism for first-trimester miscarriage in PCOS. Because glycodelin inhibits mixed lymphocyte reaction and natural killer cell activity, impaired production of glycodelin presumably allows a maternal immune response against the embryo." Cohen misses the PCOS immune connection completely.

Incompetent Cervix

Cohen's lack of understanding of the miscarriage literature comes through again in discussions about incompetent cervix as well. On page 138, he states "factors that cause the cervix to weaken largely remain a mystery." Yet he also says "some studies have shown links to other uterine anomalies, exposure to DES, and even antiphospholipid antibodies"
Why doesn't Cohen dig deeper here? If indeed he says incompetent cervix is linked to APAS, DES and uterine anomalies, how has he missed the fact that cervical incompetence is also associated with Th1:Th2 cytokine imbalance and that Th1: Th2 cytokine imbalances is associated with incompetent cervix? Doesn't he want to solve this cervical incompetence (as he puts it) "mystery"?
See supporting incompetent cervix studies that Cohen completely misses in his book:

1. Mohapeloa H et al HLA-DR typing of women with recurrent late spontaneous abortion and unsuccessful cervical cerclage. Hum Reprod. 1998 Apr;13(4):1079-82.
"The results suggest that HLA-DR-associated immunological factors might play a part in recurrent late spontaneous abortions and extremely preterm births under a cervical incompetence-like picture, at least in the subset of cases not treatable by cervical cerclage."

2. Lee KY et al: Interleukin-6, but not relaxin, predicts outcome of rescue cerclage in women with cervical incompetence. Am J Obstet Gynecol. 2004 Sep;191(3):784-9.
"Amniotic fluid interleukin-6 is increased in patients with cervical incompetence, which suggests that subclinical inflammation may contribute to cervical incompetence. Further, an elevated interleukin-6 level predicts a cerclage short-latency interval between cerclage and delivery. In contrast with interleukin-6, amniotic fluid relaxin does not appear to contribute to cervical incompetence-induced cervical dilation."

DES immune connection

Also, Cohen misses the fact that families who have used DES to prevent miscarriage may indeed have a higher incidence of immune issues (causing the miscarriages) that this "family tendency" to immune issues may be why "DES daughters" have more miscarriages, not the fact that they have been exposed to the DES in the womb? This possibility is never even considered, brought up or discussed in the book. Cohen, again, fails to address the possible immune connections in families who have used DES, leaving the total DES discussion more confused, not less.

Environment

On page 172, Cohen seems to agree that a few environmental factors may affect pregnancy outcome in certain instances: Nitrates in well water (page 172), and Bisphenol A in plastics (page 173). Nonetheless, Cohen seems uninterested in following up with these studies, he instead still prefers to dismiss the environmental idea overall. On page 174: "... miscarriages, as far as science can now determine, rarely occur because of what a woman eats or drinks, where she lives and works, and what air she breathes."
In fact, Cohen uses a (frankly, ridiculous) description as an example of pregnancy environmental durability: he describes how his grandmother jumped repeatedly off a chair in an attempt to induce a miscarriage. (page 174) This anecdote is (somehow?) used to support the idea that "the uterus, amniotic sac, and the placenta marvelously work together to prevent harm." Quite frankly, this is an embarrassing example of the typically non-scientific arguments that Cohen uses to support his journalistic angles.

Infection

Similarly, Cohen uses faulty logic when he discusses infectious agents. He admits that certain infections possibly may increase the incidence of miscarriage: page 166: "Infection may cause miscarriage "...rubella, syphilis, genital herpes, mumps, toxoplasmosis, malaria, possibly gardenerella." Yet, despite conceding this, Cohen still manages to glide over the infection/immune problem connection. (page 166: "...a few pathogens may account for a small percentage of miscarriages, although their sporadic nature means they play no important role in recurrent loss.")
In addition to pushing the infection miscarriage connection "under the table", Cohen never mentions how infectious agents may possibly stimulate the immune system to cause immune related miscarriage? In fact, the infection- immune connection is never even addressed at all? This is a glaring fault in Cohen's research, especially considering the fact there are several studies implicating the immune system as the ultimate cause of infection-related miscarriage. In fact, Dr Attila Toth of New York City has devoted whole career to this infection/miscarriage issue. Yet apparently Cohen knows nothing of Dr. Toth's research? Or if he does, Cohen chooses not to discuss it? A few infection -immune studies that Cohen misses:

1. Korbel DS et al: Natural killer cells and innate immunity to protozoan pathogens. Int J Parasitol. 2004 Dec;34(13-14):1517-28.
"Natural killer (NK) cells are lymphoid cells that mediate significant cytotoxic activity and produce high levels of pro-inflammatory cytokines in response to infection."... "NK derived interferon-gamma (IFN-gamma) production is also essential for control of several protozoal infections including toxoplasmosis, trypanosomiasis, leishmaniasis and malaria."

2. Ashkar AA et al: "Interleukin-15 and natural killer and NKT cells play a critical role in innate protection against genital herpes simplex virus type 2 infection." J Virol. 2003 Sep;77(18):10168-71. "This study demonstrates that IL-15 and NK-NKT cells are critical for innate protection against genital HSV-2."

3. Jensen JR et al: Fluctuations in natural killer cell activity in early syphilis. Br J Vener Dis. 1983 Feb;59(1):30-2. "In primary syphilis natural killer cell activity was increased, especially in patients lacking circulating lipoidal antibodies."

Luteal phase defect and progesterone

In addition to missing the infection-immune connection completely, Cohen also seems to miss the hormonal-immune connection as well. Though he says that an association may exist between luteal phase defect and miscarriage, Cohen misses (yet again) the possible immune relationship that may exist between these two issues. On page 99, Cohen states: "If the lining becomes inhospitable too early, as happens with what's called a deficient luteal phase, the embryo will not burrow, leading to a miscarriage, or it will not borrow currently, causing preeclampsia later in pregnancy"
No discussion is made about the fact that patients with poor luteal phases often have low progesterone in the latter half of the cycle...or the fact that progesterone has been shown to have an immunosuppressive effect. This immune factor may contribute at least in part to progesterone supplement's immune healing effect in recurrent miscarriage patients. See more studies that Cohen apparently misses in his book:

1. Szekeres-Bartho J. Immunological relationship between the mother and the fetus. Int Rev Immunol. 2002 Nov-Dec;21(6):471-95. "Another protective mechanism operating in favor of pregnancy is progesterone-dependent immunomodulation. Due to stimulation by fetally derived antigens, pregnancy lymphocytes develop progesterone receptors and in the presence of progesterone produce a mediator (PIBF) that, through altering the cytokine balance, inhibits NK activity and exerts an antiabortive effect in mice."

2. Laskarin G, Tokmadzic VS, Strbo N, Bogovic T, Szekeres-Bartho J, Randic L, Podack ER, Rukavina D.Progesterone induced blocking factor (PIBF) mediates progesterone induced suppression of decidual lymphocyte cytotoxicity. Am J Reprod Immunol. 2002 Oct;48(4):201-9. "The results indicate possible role for PIBF, as a mediator of progesterone in regulation of Decidual Lymphocyte cytolytic activity at the maternal-foetal (M-F) interface."

Preeclampsia

Lastly, on page 99, Cohen successfully makes the connection that patients who suffer from luteal phase defect may also suffer from preeclampsia at a higher rate. However (yet again) he totally misses the possible connection that exists between preeclampsia and immune issues (even more surprising considering the number of studies supporting the preeclampsia- immune connection that exist out there). How can Cohen miss this? Again and again it seems Cohen is totally unable to put the complex pieces of the miscarriage puzzle together. Again and again he fails to see the immune connection, failing to see how it can clarify so much of the "muddy water" that exists in this recurrent miscarriage field today. Here are some more immune/reproductive studies that Cohen completely misses:

1.Saito S, Sakai M. Th1/Th2 balance in preeclampsia. J Reprod Immunol. 2003 Aug;59(2):161-73. "Th1 predominant immunity is closely related to inflammation, endothelial dysfunction and poor placentation."

2. Makhseed M, Raghupathy R, El-Shazly S, Azizieh F, Al-Harmi JA, Al-Azemi MM. Pro-inflammatory maternal cytokine profile in preterm delivery. Am J Reprod Immunol. 2003 May;49(5):308-18.
"These data are suggestive of a maternal type 1 cytokine bias in preterm delivery".

3. Simhan HN, Krohn MA, Zeevi A, Daftary A, Harger G, Caritis SN. Tumor necrosis factor-alpha promoter gene polymorphism -308 and chorioamnionitis. Obstet Gynecol. 2003 Jul;102(1):162-6.
"Carriage of the TNFA2 allele is associated with a more than three-fold increased risk of clinical chorioamnionitis, even when accounting for important clinical and microbiologic risk factors."

4. Kaplan D. Fetal wastage in patients with rheumatoid arthritis. J Rheumatol. 1986 Oct;13(5):875-7.
"Ninety-six women with rheumatoid arthritis (RA) were found to have an abortion ratio higher than that of a comparison group (p = 0.005). This was true even before the onset of their RA (p = 0.007)"

5. Sergent F, Verspyck E, Marpeau L. [Crohn's disease and pregnancy. About 34 cases. Review of the literature] Gynecol Obstet Fertil. 2003 Jan;31(1):20-8.
"When the disease (Crohn's) is active, the risk of abortion and prematurity increases."

3. Cohen's flawed anti LIT arguments

Gullible patients

On page 58 Cohen begins: "Many couples plug their ears and firmly believe that because of the treatment, they have babies - and no amount of scientific data can shake the power of that conviction." From the beginning of the book, Cohen seems step off on the wrong foot about a typical reproductive immunology patient's psychological nature. He apparently accusing anyone who choose new or controversial treatments (like LIT or IVIG) to be emotionally gullible, unwilling (or unable?) to make sound scientific decisions. In fact, in my personal experience (through my many years watching these types of treatment programs) I have found that reproductive immunology (RI) patients are probably some of the most clear thinking, well read, well researched medical patients out there, able to pull apart any study to find its strengths, weaknesses and its flaws. Certainly most RI patients are not types to ignore solid scientific data. Already Cohen seems "off base" about the patient population he is writing about.

The REMIS LIT study by Carol Ober

Regarding the Carol Ober REMIS study Cohen states on page 69: "Because of the lack of benefit, we recommend against this intervention (LIT) as a treatment for unexplained recurrent miscarriage' concluded the researchers." It is already known that the REMIS study "proving" LIT ineffective was flawed in many ways. Dr. Beer outlined these flaws in detail in his Letter to the Editor sent to the Lancet. Among the REMIS study flaws that Dr. Beer cites are:

1. Failure to recruit an adequate number of study patients.

2. Failure to induce immune responses. Only 26% of women who received lymphocyte immunization developed HLA antibody response. (The immunization must have been prepared and/or given incorrectly to elicit this low response.)

3. 21 of 59 abortuses received genetic study. All (total 11) abnormal fetuses were from treatment group but this data was not reflected in the outcome analysis.

4. A higher proportion of treatment group had a previous live birth (P=0.054). Yet a previous meta-analysis had shown that lymphocyte immunization more effective in women with primary abortions. This was not discussed or considered in the REMIS study.

I know Cohen, through his LIT research, must have read the miscarriage support sites and Dr Beer's Lancet letter (available online to anybody), yet he makes no mention of this letter or any of its arguments in his LIT chapter. Why does he seem to avoid addressing this issue? This reporting bias not only does injustice the LIT, but also to those trying to find the truth about this LIT medicine. And frankly makes one wonder about how "impartial" Cohen's journalistic intentions really are.

Poor patient selection

Many of Dr. Beer's criticisms of the REMIS study similarly apply to other LIT studies. A common flaw found in negative outcome LIT studies is the failure to test subject's LAD (blocking antibody) levels before and after the LIT injections. As a result, researchers never really know if LIT patient:

1. Really needs LIT
2. Has achieved a proper LIT response before conception is attempted

In addition to these flaws, some LIT studies fail to use fresh donor cells (such as the REMIS study), making LIT less effective. Other studies fail to follow the timing and dose requirements that Dr. Beer recommends (i.e. some studies only do LIT once preconception, some studies do not wait the 3- 4 weeks necessary for the proper immune response take place). Lastly, those who understand reproductive immunology understand that LIT should be not be used as the sole immune treatment. Other immune problems need to be identified and independently treated as well (e.g. APA issues, ANA issues, cytokine imbalance, etc). Essentially, patients need a full immune work-up before doctors decide how LIT will fit into their total immune protocol. See Christiansen et al: Evidence-based investigations and treatments of recurrent pregnancy loss. Fertility and Sterility, Volume 83, Issue 4, April 2005, pages 821-839. Study quote: "Current meta-analyses evaluating the efficacy of treatments of RPL are generally pooling very heterogeneous patient populations and treatments. It is recommended that future meta-analyses look at subsets of patients and treatment protocols that are more combinable."

Cohen criticizes the use of anecdotal evidence yet uses anecodotal evidence himself

On page 74 Cohen criticizes the LIT studies as being flawed saying, "the fuzzy scientific rationale behind theories often makes it difficult to select patients who indeed may benefit from a treatment." Yet at the end of the same chapter, on page 82, he uses the example of a solitary successful pregnancy (Jess') that succeeded without LIT use, saying this success "casts further doubts about whether the value of lymphocyte immune therapy"
So Cohen uses one solitary pregnancy success to "further cast doubts" on the value of LIT? He admits the success is anecdotal, yet still uses it as an emotional tool to bash LIT at the end of his chapter. Again Cohen seems to push non-scientific thinking here. How are readers supposed to respect the author as a scientifically unbiased journalist when so much emphasis is placed on the emotional power of the single success story, to pull the emotions of the reader at the end?
Also, it should be noted, if Cohen had any true understanding of LIT, he would recognize that blocking antibodies built of from Jess's previous successful pregnancy would have alone explained her second pregnancy success without LIT. Yet this possibility is not even touched upon in the chapter because Cohen apparently does not understand the LIT science (either "does not understand" the issue or chooses to skip over the issue altogether?) In either case, from a reproductive immunologist's point of view, this LIT chapter ends on a very weak note.

The Tender Loving Care (TLC) argument

Last but not least, we must talk about the author's focus on "Tender Loving Care" (TLC) Cohen's "beloved" argument that he seems to like to use to dilute the validity of many miscarriage studies in the book. Throughout the book, it is evident that Cohen has been rather "sucked in" by the Tender Loving Care argument, the idea that offering extensive psychological support and emotional support to a patient can significantly increase a patient's likelihood of pregnancy success.
On page 175, Cohen calls the Liddell TLC study, "a study with spectacular powers." In a RESOLVE Interview Cohen calls Dr. Lesley Regan's 1997 TLC study "an amazing study. I learned more from it than maybe any single paper (and I have read maybe1000). I highly recommend it." Essentially Cohen has three studies to back his TLC argument:


1. Liddell HS et al: Recurrent miscarriage--outcome after supportive care in early pregnancy. : Aust N Z J Obstet Gynaecol. 1991 Nov;31(4):320-2.
86% success with TLC (38/44)
33% success without TLC (3/9)

2. Clifford K et al: Future pregnancy outcome in unexplained recurrent first trimester miscarriage. Hum Reprod. 1997 Feb;12(2):387-9.
74% success with TLC (118/160)
49% success no TLC (20/41)

3. Stray-Pedersen B et al: Etiologic factors and subsequent reproductive performance in 195 couples with a prior history of habitual abortion. Am J Obstet Gynecol. 1984 Jan 15;148(2):140-6.
86% success TLC (no actual pregnancy numbers given in this abstract)
33% with no TLC

At first glance, these success numbers seem surprising, even shocking and impressive considering the "vague", "touchy-feely" nature of the TLC subject matter. But looking deeper in the methodology of these studies, we find the statistics are probably more deceiving and more flawed than we know. First, all the patients in each of these studies were "self selected" to receive TLC from the clinic. Populations were not randomized at all, which, of course, is a Big Red Flag to anyone trying to get meaningful scientific results. So you have to ask yourself, given the fact these TLC populations are "self selected", what reasons could cause one patient to "select" to discontinue medical care while another patient chooses to continue it? Could it be that patients whose pregnancies succeed may be more inclined to stay with the clinic, while those that are having negative experiences tend to drop out of a program with higher frequency? This is not TLC are we are measuring here. It could be a measurement of an interesting tendency to "hide" and "grieve" in human nature.
Also, another point to note about these TLC studies: in not one of these TLC studies is the actual "Tender Loving Care" procedure exactly outlined. What does this TLC actually involve physically? There may be factors involved in these TLC pregnancy successes apart from the TLC itself, factors we could never pick up on because they are not outlined for us? This description deficiency is yet another red flag with these studies.

Dr. Beer's success due to TLC?

Last, but not least, it appears that Cohen sees Dr Beer's program through "TLC tinted glasses" as well. See Cohen's quote on page 82: "I suspect that he (Dr. Beer) does offer tender-loving care, and that its benefits may confuse the results his patients experience with experimental treatments." In making this statement, Cohen clearly reveals his lack of familiarity with the day to day running of Dr. Beer's program. One thing most of Beer patients know, only a small percentage of Dr. Beer's registered patients actually ever meet Dr. Beer in person. Most of Dr. Beer's consults are conducted by phone or by email. In fact, Dr. Beer only meets about 5% of his registered patients "in person" at all. Many of these patient meetings are "one time only" personal meetings with later consults being done over the phone or through email. Certainly, Dr. Beer does not have ongoing basis face to face relationship with most of his patients, unless one considers emails "TLC." All in all, Cohen puts these TLC studies on a pedestal in a way he rarely does with other studies in the book. Cohen's later words about the TLC studies are even more revealing:
Page 179: "Just as scientific research can never prove that love exists, I suspect it can never arrive at rock solid evidence that expert care prevents miscarriage or helps people come to terms with their reproductive fate. But as one researcher said to me, If you witness a talking dog, you do not need a control group to believe it. In three different recurrent miscarriage clinics around the world, I have seen the equivalent of a talking dog"
How can you argue with someone who has decided that controlled studies are no longer necessary to prove a theory valid? This is the same man who says we should dismiss LIT because the studies are flawed? A man who believes that TLC is as obvious because it is like a "talking dog"? It scares me, frankly, that Cohen is writing a book we are supposed to take seriously, that the world is supposed to take seriously, when he openly admits to using a "talking dog" type of reasoning.

Finally, Cohen's most heartfelt speech in his book, making the strongest veiled attacks on any miscarriage patient's decision to use immune therapy are found on page 129: "Women and men who want babies, especially those who have tried and failed, would benefit if they recognized how intense desires can lead them to take unnecessary risks. It bears repeating again and again and again. Most women who miscarry even three or four times, will carry to term if they become pregnant again...they (millions of women) may logically end up in the delivery room praising an intervention that, years later, they will come to curse." What does this mean, praising an intervention "in the delivery room" that, years later, "they will come to curse"? Does this mean, even after delivering our "Beer babies" using immunotherapy, we will feel we made the wrong decision to do LIT and IVIG? Please! I just hope that others can see through the facade of this book the way that I do.

As I hold and play with my "Beer babies" each day, after suffering devastating losses, I feel blessed that I myself, at least I have put the scientific connections together. That I, myself, at least, have seen the patterns, seen the immune connections, as a result, understand the bigger miscarriage picture in a much more complete way.
Pity those who read this book and come away feeling more confused about immune therapies than they were before. Pity them. Pity Cohen for bringing this situation about. However, in the big picture, I am not worried. I honestly feel that so much progress has been made in this reproductive immunology field the last few years, that the blind, anecdotally-based musings of a sensationalist reporter will do nothing to hurt the field over the long term. The foundation of the RI science is far too reaching, far too strong to ever be marred by the non-scientific ponderings that are really so biased that most (if not all) true scientists will see right through them upon reading this very dangerously naïve and misleading book.

-An informed RI Advocate and Dr Beer patient

I purchased this book intending to get an unbiased view of the Spanish exploration of the New World. That is a difficult task given the nature of 20th & 21st Century academia.

This text, an eye witness account of what happened on real explorations, more than satisfies my objective. What's more, it's as exciting as can be... kind of like Star Wars... exploring new worlds, defeating the bad guys and establishing new alliances.

Excellent work.

If I could rate this work greater than five stars, I would. Not that it's the most erudite of tales but simply because it is the truth as Bernal Diaz experienced it. Almost certainly, it isn't one hundred percent accurate for Diaz' experiences are necessarily modified by the years separating his experiences from his writing of it. Nor was he, or any other member of the Cortez' expedition, an anthropologist, ethnographesr, scientist or even a particularly accurate observer. They were simple men--brave men, brutal men, trapped men--bent on plunder.

Still the Bernal Diaz memoirs are as good as it gets regarding the Conquest of Mexico and, as such, is an invaluable account. I find his account so important that I used it as my primary source in researching my novels--"Skull Rack" and "Hummingbird God"--on the Conquest of Mexico. I loved it when Diaz remarks towards the end of his account that, even in his old age, he wasn't able to sleep the night through. He "had to get up and look around." It's fascinating to note that basic human nature doesn't really change. Bernal Diaz del Castillo was suffering from post-traumatic stress disorder induced by the fearful events of his two year battle in Mexico. Also, I loved it when he commented--also toward the end of his tale--that "although we robbed the Indiains, Cortez robbed his soldiers even more."

Cortez, for all his brillianace, luck and perseveranace, was, at the end, nothing more than a common thief.

Ron Braithwaite

When I first read the 1800 English translation, I could not put it down. Here are the first lines--a real grabbers! "In the year 1514, I left Castile (Spain) in company with Pedro Arias de Avila, who was then appointed governor of Tierra Firma (east Panama)...but afterwards suspicious that his son-in-law had an intention of revolting, he caused him to be beheaded."

Bernal's description of the Aztec city of Tenochtitlan is amazing: "To many of us it appeared doubtful whether we were asleep of awake; nor is the manner in which I express myself to be wondered at, for it must be considered, that never yet did man see, hear or dream of anything equal to the spectacle which appeared to our eyes on this day."

And how about this magnificent line: "And now, let who can, tell me, where are men in this world to be found, except ourselves, who would have hazarded such an attempt."

And here is the horrific vision the Spaniards beheld when they climbed to the top of the great Aztec temple-pyramid. Remember that nearby, and looming up like a nightmare, was the stupendous "tzompantli," or skull rack. By careful Spanish count, it contained the grinning remains of 136,000 human beings.

"In this place they had a drum of most enormous size, the head of which was made of the skins of large serpents: this instrument when struck resounded with a noise that could be heard to the distance of two leagues, and so doleful that it deserved to be named the music of the infernal regions; and with their horrible sounding horns and trumpets, their great knives for sacrifice, their human victims, and their blood besprinkled altars, I devoted them, and all their wickedness to God's vengeance, and thought that the time would never arrive, that I should escape from this scene of human butchery, horrible smells, and more detestable sights."

The Conquest takes on a different color when seen through the eyes of the Spanish. Yes, they were greedy and cruel, but the scale of human sacrifice practiced by the Aztecs was beyond imagination. It is said that some twenty thousand people were sacrificed for the dedication of the Temple of the Sun. The Aztec priests worked for hours on end cutting out human hearts. They worked until they collapsed from exhaustion.

Bernal's history is also interesting for another entirely different reason. Joseph Smith (born 1805), the Mormon prophet, came of age during the period of English translations of Spanish histories (Bernal's in 1800 in London, and 1803 in the US, and Clevigero's "History of Mexico" in 1806 in Virginia and 1817 in Philadelphia).

Therefore, the golden splendor of the Spanish conquests of Mexico and Peru was fresh on everyone's mind, especially because the Spanish colony of Florida had become an American state (1821).

Thus, any notion that Americans were unaware of the great civilizations of ancient America is without foundation in real history. Ancient civilizations in America were so on the mind of people that in 1816, Solomon Spaulding wrote a history about a white and dark race in ancient America. His novel, "Manuscript Found," had the white race of mound builders destroyed by a darker-skin race.

Read my review of Robert Silverberg's magnificent book, "The Mound Builders of Ancient America: The Archaeology of a Myth." A must-read for anyone interested in the archaeology and myths about ancient America. Click here: Mound Builders

First person historical accounts are generally the best way to read history and have it come alive in the mind of the reader. This book by Bernal Diaz is certainly no exception to that rule. Although Diaz wrote this much later in life, and doubtless his memory was not perfect, it is obvious that the experience of marching with Cortez in the conquest of the Aztec empire left innumerable vivid memories in his mind.

I am very sensitive to the fact that the conquest of the Aztec empire and other native empires in the Americas left a horrific legacy which is still felt dramatically throughout the hemisphere. Despite the fact that in many ways, the conquistadors should not be considered "heroes," I think we still can admire and be awed by their courage and fortitude in the face of unbelievable odds in facing the Aztecs and not only escaping with their lives, but eventually conquering the entire civilization. Diaz brings these events to life better than any history book I ever read, and I highly commend this book to anyone interested in the history of this period, of Mexico, or Latin America in general.

Diaz was one of the soldiers who accompanied Cortez to invade the Aztec Empire. His account is one of the best we have of the whole affair. It is not written with much bias and was written to discount historical myths after the invasion had taken place. It is very analytical at times and his analysis of what happened is given added authority since he was present at the events. If you want to understand what happened this is a great book to read.

If you are a fan of Dr.McDougall, you will know that he recommends a plant based diet to cure disease. He explains in great detail along with humorous cartoons to get the message across as to what causes constipation, diverticulits, colitis and so much more. Eat your plants and you won't end up like the cartoon characters, overweight and miserable.

I would also like to add that the more natural your diet is, the better for you and you feel fantastic. If you feel that eating a plant-based diet is a horrible thing to do, then you aren't creative. You don't just put veggies on your plate..you create wonderful and delicious recipes. There are so many sites online to find great vegan and raw recipes.
I recommend getting a powerful blender and a food processor. With those two gadgets you can make delicious soups, smoothies, sauces, ice cream, pudding, and so much more. You will never miss your old way of eating, and you will stay regular, your skin will clear up, and you will have more energy than ever before. Guaranteed.

Our standard American diet can result in many digestive ailments for adults and kids. This book has helped many of my clients get back on track.

book, I haven't really had a chance to read much of the book. what I have read seems interesting.

I've been an avid follower of Dr. John McDougall since he first published 'The McDougall Plan' and 'A Challenging Second Opinion' in 1983-85.

The man does his homework. His books are well researched. In 'Digestive Tune-Up' - pages 159-204 are his notes and references.

This book is up to his usual standard of excellence - AND, it's easy to read and understand.

I heartily recommend it.

I've followed McDougall's program for 15 years...and many people ask how I'm able to stay so fit and healthy. I'm certain I've converted at least 20 others...but there are at least 20 others who started and can't seem to stay on the program. They think it's too hard.
To me, it's easy. Just eat the RIGHT things, and don't worry about how much you eat. If you have a big appetite, it's no problem! Tell people you are under doctor's orders at restaurants or parties.
I'd much rather trade in the fats, meats, and cheeses for ideal weight and good health. I'm over age 55 and I don't take any medications or diet pills -- and I eat as much as I want. My blood pressure, other tests are normal. I wear a size 8, which is smaller than I was at age 35.
I real all McDougall's books because they educate and inspire me. Go to his website, read the forum there. Great information.